The Preconditioning and Stress Relaxation of Skin Tissue
نویسندگان
چکیده
This paper reports our recent study on the preconditioning effects and stress relaxation behaviour of fresh swine skin. Uniaxial cyclic tensile loading and stress relaxation tests were performed with swine skin samples in two different directions to study the effects of fibre direction on mechanical properties. With stress relaxation tests, skin samples were loaded to different strains to observe its effects on stress relaxing over time. Mathematical modelling was performed to compare the data obtained from stress relaxation tests. Fibre direction effects were demonstrated in results of cyclic preconditioning as well as stress relaxation tests. The stress relaxation experimental results indicated that strain and time independency only appears at certain strain levels. The skin tissue has stress relaxation characteristics at strain of 15% and below. Under such strain amplitudes, the samples exhibited greater stress decaying rate in the first 200 seconds of the relaxation period, and began to approach steady decay after 200 seconds. With quasi-linear viscoelastic theory and reduced relaxation function, the modelling has adapted the experimental data sufficiently. This study is a significant step towards understanding skin tissue rheological behaviour and its multidiscipline properties.
منابع مشابه
Effects of saffron oral gavage on protection of skin flaps against tissue necrosis and oxidative stress in rats
Introduction: Today, skin flaps are used in many reconstructive surgeries and healing of skin lesions as one of the main methods of treatment. Despite improvements in the fields related to enhancement of skin flap survival, flaps viability and their efficacy are still threatened with issues such as ischemia-reperfusion, oxidative stress, tissue necrosis, and even apoptosis in the affected tissu...
متن کاملInvestigating the role of acute and repeated stress on remote ischemic preconditioning-induced cardioprotection
Objective(s): To study the effect of acute and repeated stress on cardioprotection-induced by remote ischemic preconditioning (RIPC).Materials and Methods: RIPC was induced by giving 4 short cycles of ischemia and reperfusion, each consisting of five min. The Langendorff’s apparatus was used to perfuse the isolated rat hearts by subjecti...
متن کاملHistopathological Investigation of the Effect of Ozonated Water on Skin Ulcer Healing Process in Isolation Stress Mouse Model
Background and Objective: Skin ulcers and their slow healing are considered as one of the important medical aspects. Nowadays, various antibiotics and materials are used to accelerate the wound healing process. One of the methods taken in the field of wound healing is using ozone. On the other hand, one of the factors that hurt the speed of wound healing is stress. Therefore, the present study ...
متن کاملChronic Morphine Preconditioning: Interaction of mTOR and iNOS in protection against Ischemia/Reperfusion injury
Chronic morphine (CM) treatment increases the phosphorylation of the mammalian target of rapamycin (mTOR), which confers neuroprotection against ischemia/reperfusion (I/R) injury. Besides its important regulatory role in the proliferation, metabolism, and survival of cells, the mTOR is critically involved in intracellular signaling events during I/R injury. In the present study, we investigated...
متن کاملChronic Morphine Preconditioning: Interaction of mTOR and iNOS in protection against Ischemia/Reperfusion injury
Chronic morphine (CM) treatment increases the phosphorylation of the mammalian target of rapamycin (mTOR), which confers neuroprotection against ischemia/reperfusion (I/R) injury. Besides its important regulatory role in the proliferation, metabolism, and survival of cells, the mTOR is critically involved in intracellular signaling events during I/R injury. In the present study, we investigated...
متن کامل